In his pre-tournament news conference in Toronto on Sunday, Nadal said a recurring foot issue he has been dealing with since 2005 returned at the French Open, where he fell to eventual champion Djokovic in the semi-finals.
Top seed Carlos Alcaraz dominated Gael Monfils 6-2 6-4 and fourth seed Alexander Zverev escaped a tight first set en route to a 7-6(4) 6-3 win over Christopher Eubanks to reach the last 16 at the Miami Open on Monday.
Djokovic beats Wawrinka just before closing time
Roger Federer said he is "definitely" intending to return to top-level tennis in 2023, but added that he had not made any concrete plans beyond his scheduled appearances at the Laver Cup and his home tournament in Basel later this year.
The Russian ended Djokovic's hopes of completing a sweep of all four Grand Slam titles in 2021 when he defeated the Serb in the US Open final in September to pick up his maiden major.
'The Laver Cup next week in London will be my final ATP event. I will play more tennis in the future, of course, but just not in Grand Slams or on the tour.'
In the ongoing Monte Carlo Masters, Jannik Sinner clinched a hard-fought win as Casper Ruud crashed out.
Here is a compilation of some of the best photos from 2021...
Danish teenager Holger Rune fought back from a set down to beat hot favourite Novak Djokovic 3-6, 6-3, 7-5 and win his first Masters title in Paris on Sunday.
Evans, who recovered from illness to be part of the $15 million prize money event, showed his battling qualities to overcome Ramos-Vinolas
'During the grass court season, I unfortunately experienced a setback with my knee, and have accepted that I must withdraw from the Tokyo Olympic Games.'
Roberto Bautista Agut predicted a great future for Jannik Sinner after going down to the Italian teenager
Federer may never glide across it as only he can, or any other Grand Slam court for that matter, again. But his legacy will never fade.
Daniil Medvedev was knocked out in the fourth round of Indian Wells by Bulgarian Grigor Dimitrov on Wednesday as the world number two's near-flawless start turned nightmarish in a 4-6, 6-4, 6-3 defeat.
World No 1 Carlos Alcaraz fended off in-form American Tommy Paul to reach the Cincinnati Open quarter-finals on Thursday
Djokovic did not do much wrong as he battled Sinner and the crowd - regularly jesting with the fans who jeered him throughout the duel.
In the women's draw, Angelique Kerber was knocked out in a 6-3, 6-1 defeat to Czech Katerina Siniakova while Coco Gauf won her first ever match on clay.
The 'Big Three' of men's tennis have found some "fresh energy" to thwart the charge of younger players on the tour, world number one Novak Djokovic said after setting up yet another title clash against his biggest rival against Rafael Nadal.
A round-up of all the tennis action from around the globe.
Defending champion Stefanos Tsitsipas came out on top from a thrilling quarter-final clash with Diego Schwartzman, prevailing 6-2, 6-7(3), 6-4 on Friday to set up a meeting with Alexander Zverev at the Monte Carlo Masters.
Claycourt master Rafael Nadal quickly adapted to his new surroundings at Roland Garros with a 6-2, 6-1, 6-3 demolition of German qualifier Yannick Hanfmann in the first round of the French Open on Monday.
A look at Roger Federer's worst five Grand Slam losses.
The Spaniard needed less than 90 minutes to dispatch the 23rd seed from Italy
Alcaraz outlasts Hurkacz, Ruud stunned at Canadian Open
Images from Day 5 of the 2023 Australian Open at Melbourne Park on Friday.
World number three Roger Federer is playing his first tournament on clay for three years as he prepares for the French Open.
Earlier, title holder Borna Coric beat American Sebastian Korda 7-6 (5), 6-4, while another home hope Taylor Fritz survived a first-set thriller to beat Czech Jiri Lehecka 7-6 (14), 6-2.
Roger Federer was made to work hard by Fernando Verdasco before beating the Spanish veteran 6-3, 3-6, 6-3 on Wednesday to reach the quarter-finals of the Dubai Duty Free Tennis Championships.
'My arm has been -- I have had an issue there for quite a while now. It has gotten bigger in the last couple of weeks, so I'm just trying to protect it.'
Novak Djokovic continues his hunt for a fifth straight Wimbledon title and eighth overall to equal Roger Federer's record haul when the Serbian meets Jannik Sinner.
World number one Ash Barty delighted the Memorial Drive crowd by breezing through to the Adelaide International semi-finals with a comfortable 6-3, 6-4 victory over Sofia Kenin on Friday.
IMAGES from Day 9 of the French Open at Roland Garros in Paris on Monday.
Nadal has won the Australian and the French Open back-to-back and has the chance to become the first man to win all four majors in the same year
Muguruza wins all-Spanish clash with Badosa at WTA Finals
World number one Novak Djokovic produced a majestic display in a 7-5, 6-3 victory over American John Isner on Thursday to extend his winning streak in Asia.
Alexander Zverev overcame late nerves to beat world number one Novak Djokovic on Saturday and set up a final showdown with Daniil Medvedev at the ATP Finals.
Jabeur advances to first WTA 100 final in Madrid in style.
The unseeded Indo-Canadian pair defeated their fancied rivals 6-3, 3-6, 10-5 in a round of 16 tie of the ATP Masters 1000 event.
20-time Grand Slam champion Roger Federer returned from more than a year away for a last dance in tandem with great rival Rafael Nadal on a gripping and memorable finale by the Thames in front of a 17,500 sell-out crowd at London's O2 Arena on Friday.
World number one Novak Djokovic extended his winning run in Asia when he strolled into the last-16 of the Shanghai Masters.